Kaley Cuoco Says She Was 'Totally' Out of Her Element While Kaley Cuoco Cuoco's sexual orientation remains a topic of interest among fans and the press. Given her amazing career as well as talent, she has always managed to keep her personal life private. However, many wonder about her relationships and explore her preferences in terms of romance. The reality remains unconfirmed, but it's important to respect her personal choices and appreciate on her exceptional skills in the acting world.